Among the ameloblastomas, the desmoplastic variation is rare. The desmoplastic ameloblastoma (DA) is characterized by specific clinical, imaging, and. Desmoplastic ameloblastoma (DA) is a rare variant of ameloblastoma, and less than patients have been reported in the literature. The present case. Desmoplastic Ameloblastoma is a rare variant of ameloblastoma. 90 cases of desmoplastic ameloblastoma have been reported so far in literature. We are.

Author: Nile Mazurg
Country: Denmark
Language: English (Spanish)
Genre: Education
Published (Last): 13 April 2014
Pages: 429
PDF File Size: 8.34 Mb
ePub File Size: 10.31 Mb
ISBN: 875-9-18557-124-9
Downloads: 25338
Price: Free* [*Free Regsitration Required]
Uploader: Meztishura

Immunohistochemical demonstration of keratin in ameloblastoma as an indication of tumor differentiation. On extraoral examination, noticeable facial asymmetry ameloblastma observed due to swelling present on the right side of the mandible.

Analysis of 17 Nigerian cases Effiom, O. Pathology of the desmoplastic ameloblastoma. Oral and maxillofacial pathology. No lymphadenopathies or fistulae were present.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.

Case Reports in Pathology

Ann Maxillofac Surg ;3: Differences in expression are attributed to diverse factors such as dedifferentiation or rate of proliferation of neoplastic cells, inherent cellular potential, or extracellular mediators. Ameloblastoma clinical, radiographic and pathologic study of desmoplastic ameloblastoma, J Oral Maxillofac Surg, To receive news and publication updates for Case Reports in Pathology, enter your email address in the box below.

Pathology and Genetics of Head and Dwsmoplastic Tumors.

The mixed radiographic appearance is due to osseous metaplasia within the dense fibrous septa that characterizes the lesion, and it is not because of the production of a mineralized product by the tumor. The present case was treated conservatively with the aim of maintaining quality of life by focusing on aesthetics and function.


A previous study reports that DA tends to be less biologically aggressive than conventional ameloblastoma based on their estimated mean growth rates [ 5 ]. National Center for Biotechnology InformationU. The central area consists of swirled, hypercellular, spindle-shaped, or squamous epithelial cells. As desmoplastic ameloblastoma is an uncommon lesion, it warrants proper diagnosis and treatment.

Desmoplastic ameloblastoma

Un raro caso clinico]. Unicystic ameloblastoma of the mandible–an unusual case report and review of literature. None, Conflict of Interest: Also, the very thin cortical bone of the maxilla forms a weak barrier for the spread of tumors. Similarly, it has been reported that connective tissue stroma in desmoplastic ameloblastoma exhibited a strong positive reaction for collagen type VI. Biological profile based on cases from the literature and own files.

A case report and literature review. Metaplastic bone formation has been reported in few cases. Involved teeth may be displaced with cortical plate expansion.

Follicular ameloblastoma figure 1. The epithelial cells at the periphery of the islands are cuboidal and occasionally show hyperchromatic nuclei. The histopathology of the lesion was characterized by a stroma containing abundant collagen fibers and scattered tumor nests or strands composed of spindle-shaped odontogenic epithelial cells. Related articles Desmoplastic ameloblastoma. Int J Oral Maxillofac Surg.


J Oral Maxillofac Pathol. She denied experiencing any bleeding, pain or sensory changes. Amelob,astoma view showing right nasal floor involvement Click here to view.

Since then, there had been gradual increase in the size of swelling to its present size. We performed a clinicopathological analysis of the approximately 30 cases of hybrid ameloblastoma reviewed by Rai et al.

Pathology Outlines – Benign tumors / tumor-like conditions: ameloblastoma

Received Jan 26; Accepted Apr Moreover, the radio-graphic features of this lesion rarely point towards ameloblastoma. Although some cases of squamous odontogenic tumor may have an aggressive clinical course, the currently preferred treatment is curettage, which is followed by few recurrences.

Ameloblastoma is the most common borderline odontogenic tumor of epithelial tissue origin.

Sign up for our Email Newsletters. Desmoplastic variant of ameloblastoma in Malaysians.

Usually asymptomatic and can be found incidentally on routine dental examinations Can also present as a painless swelling or expansion of jaw Pain and paresthesia are uncommon Slow growing, rarely metastasizes to lungs or CNS Metastases associated with tumor of long duration, multiple surgical procedures, radiation therapy Associated with nevoid basal cell carcinoma Gorlin syndrome Fam Cancer ; In recent years, the histomorphological spectrum of ameloblastoma has expanded to include a desmoplastic variant.