Chlorothiazide should be used cautiously in patients with renal disease resulting in severe renal impairment because the drug decreases the glomerular. Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Diuril (Chlorothiazide). Chlorothiazide sodium for injection, USP is a diuretic and a vial containing: Chlorothiazide sodium equiva- . toxicity. Refer to the package insert for lithium.
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The first dose response acute postural hypotension of prazosin may be exaggerated in patients who are receiving beta-adrenergic blockers, diuretics, or other antihypertensive agents. Sodium picosulfate; Magnesium oxide; Anhydrous citric acid: Cumulative effects of the drug may develop in patients with impaired renal function.
Dilution Chlorothiazide – GlobalRPH
Children 2 to 12 years. Moderate Concomitant administration of hydrochlorothiazide to patients receiving nondepolarizing neuromuscular blockers e. Correct hypokalemia and hypomagnesemia before pasireotide receipt. In addition, thiazide diuretics, like hydrochlorothiazide, can cause hyperuricemia.
Moderate Patients receiving a diuretic during treatment with venlafaxine may be at greater risk of developing syndrome of inappropriate antidiuretic hormone secretion SIADH. Photosensitivity has been reported with thiazide diuretics. In general, patients with a documented sulfonamide allergy are considered to be predisposed for development of allergic drug reactions. For single dose only. Thiazides have been shown to increase the urinary excretion of magnesium; this may result in hypomagnesemia.
Because chlorothiazide sodium for injection contains no preservative, a fresh solution should be prepared immediately prior to each administration, and the unused portion should be discarded.
Although any chloride deficit is generally mild and usually does not require specific treatment except under extraordinary circumstances as in liver disease or renal diseasechloride replacement may be required in the treatment of metabolic alkalosis.
Moderate Pentoxifylline has been used concurrently with antihypertensive drugs beta blockers, diuretics without observed problems. Information on oral dosing in this age group is supported by evidence from empiric use in pediatric patients and published literature regarding the treatment of hypertension in such patients.
Although the clinical significance of these effects is unknown, use caution when coadministering beta-agonists with thiazide diuretics and monitor serum potassium as clinically indicated. Neonates pacmage Infants younger than 6 months. In addition, diuretics reduce the risk of stroke and cardiovascular disease in patients with diabetes.
Measure potassium concentrations at baseline and periodically during dichlorphenamide treatment.
Diuril Oral Suspension mg/5mL, 8 oz. Bottle
Thiazide diuretics can cause hyperuricemia. Minor Coadminisitration of thiazides and prokinetic agents may result in decreased bioavailability of the thiazide diuretic. Moderate Thiazide diuretics can enhance the hypotensive effects of antihypertensive agents or diuretics if given concomitantly. Thiazides may worsen dilutional hyponatremia, especially in elderly individuals.
The degree to which chlorothiazide is removed by hemodialysis is unknown. Lithium generally should not be given with diuretics.
Warning signs or symptoms of fluid and electrolyte imbalance, irrespective of cause, include dryness of mouth, thirst, weakness, lethargy, drowsiness, restlessness, confusion, seizures, muscle pains or cramps, muscular fatigue, hypotension, oliguria, tachycardia, and gastrointestinal disturbances such as nausea and vomiting. Minor Because inzert is nephrotoxic, concurrent or subsequent administration of other nephrotoxic agents e.
Thus, caution is advisable when silodosin is administered with antihypertensive agents. Hypersensitivity to any component dkuril this product or to other sulfonamide-derived drugs. Use with particular caution in hypertensive patients with high or uncontrolled blood pressure.
Additive reductions in blood pressure may be seen when fish oils are used in a patient already taking antihypertensive agents. Some patients develop significant hypotension shortly after administration of the first dose. Extravasation must be rigidly avoided. Major Use of cocaine with antihypertensive agents may increase the antihypertensive effects of the antihypertensive medications or may potentiate cocaine-induced sympathetic stimulation. Moderate Hawthorn, Crataegus laevigata may lower peripheral vascular resistance.
Thiazides may decrease urinary calcium excretion. Moderate Baclofen has been associated with hypotension. Moderate Caution is advised when using droperidol in combination with thiazide diuretics which may lead to electrolyte abnormalities, especially hypokalemia or hypomagnesemia, as such abnormalities may increase the risk for QT prolongation or cardiac arrhythmias.
Symptomatic hyponatremia may require discontinuation of mirtazapine, as well as implementation of the appropriate medical interventions. Moderate Morphine may reduce the efficacy of diuretics due to induction of the release of antidiuretic hormone.